Jeremy Chopek, Ph.D.

Assistant Professor, Physiology & Pathophysiology

University of Manitoba

Accepting Graduate Student
The Chopek lab is currently accepting graduate students for Fall 2019 and Early 2020 admission.
Please contact Dr. Chopek by email to enquire
Dr. Chopek’s Brainstem-Spinal Neural Networks for Movement Laboratory
406 BMSB
204-789-3855
Research
Dr. Chopek received his MSc (2009) in Kinesiology and PhD (2014) in the Department of Physiology & Pathophysiology, University of Manitoba under the supervision of Dr. Phillip Gardiner, in the Spinal Cord Research Centre. Dr. Chopek’s work examined how motor circuits were affected following spinal cord injury and exercise by examining alterations in motoneuron biophysical properties, stretch reflexes, gene expression and sensitivity to pharmacological agents.

Dr. Chopek completed a post-doctoral fellowship at Dalhousie University (2014-2018), Department of Medical Neuroscience working with both Dr. Zhang and Dr. Brownstone at University College London. His work has begun to characterize and understand microcircuit formation in both the medulla reticular formation, a centre vital for the initiation of movement and the lumbar spinal cord, the area in which movement is produced. To achieve this, he uses a combination of transgenic mouse lines, optogenetic or photo-manipulation of single cell or whole cell populations, in-vitro electrophysiology, viral tracers and confocal microscopy. To date, he has subdivided the chx10 neuronal population in the brainstem into two distinct cell populations based on their morphology, biophysical properties, connectivity and projection patterns. In addition, he has also found a novel connectivity pattern of the spinal V3 interneuron population, which in addition to forming commissural connections also synapse locally with ipsilateral motoneurons.

Dr. Chopek joined the Department of Physiology & Pathophysiology and the Spinal Cord Research Centre on September 1, 2018.

Areas of Expertise
Brainstem-spinal cord in-vitro electrophysiology, neuronal microcircuit formation, optogenetic and photomanipulation, transgenic mouse models, viral tracers, confocal micrscopy, chx10 brainstem neurons, spinal V3 interneurons, in-vivo electrophysiology, spinal cord injury and exercise, stretch reflexes, gene expression.
Publications
Search PubMed for publications by Chopek J
See Also
Dept. of Physiology & Pathophysiology profile for Dr. Chopek